Two randomized controlled trials have been published in the recent past, one last year, and the other just a few months back, that look at the effectiveness of curcumin as a treatment for knee pain, and more specifically for knee pain induced by osteoarthritis.
A few months back I wrote an article about the state of the evidence on face masks. At that point, there were no good studies looking at the effectiveness of face masks in preventing the spread of covid-19 specifically, but there was a systematic review that looked at all randomized trials that had been done on face masks for the prevention of respiratory infections more generally. That review found that surgical face masks reduced the probability of getting a respiratory infection by around 4% in absolute terms (17% in relative terms).
I’ve been getting questions about long covid and my standard answer has been that I don’t think it’s any different from post-viral syndrome, a condition that affects some people after a viral infection but that usually clears up within a few months. I’ve been generally sceptical of claims of long covid as some distinct entity for a couple of reasons.
One problem with all the trials of statins is that they look at the probability of still being alive after x years. But that’s not really the question patients want answered. Patients want to know how much longer they can expect to live if they take a statin every day for the rest of their lives. Is it weeks? months? years? decades?
A very interesting article was recently published in Lancet that sought to understand which factors correlate, on a country level, with covid related outcomes. The study was observational, so it can only show correlation, not causation, but it can still give pretty strong hints as to which factors protect people from covid, and which factors increase the risk of being harmed.
One of the most frequent questions I’ve been getting recently is how accurate I think the covid tests are, and in particular the PCR tests. As it happens, a systematic review has recently been published in Evidence Based Medicine that looks at the covid tests (both PCR and antibody), so I thought it would be interesting to look in to the evidence together. This article gets a bit technical and math-heavy in places, so please bear with me. I think the payoff is worth it.