Over the last two months I’ve literally been bombarded by people asking me about my opinions on ivermectin as a treatment for covid, so I figured I’d better look in to it. Ivermectin is an anti-parasitic drug, used primarily to treat infections caused by parasitic worms. It was discovered in the 1970’s, and the researchers who discovered it were awarded the Nobel prize for their discovery in 2015.
Three separate covid vaccine trials have now had their results published in peer-reviewed journals (Astra-Zeneca, Pfizer, and Moderna), and the vaccines have already been approved for use in multiple countries. In light of that, I think it’s time to look in to how effective and safe the vaccines are, especially considering that many of us are about to be given the option to take them (and some of us already have).
Two randomized controlled trials have been published in the recent past, one last year, and the other just a few months back, that look at the effectiveness of curcumin as a treatment for knee pain, and more specifically for knee pain induced by osteoarthritis.
One problem with all the trials of statins is that they look at the probability of still being alive after x years. But that’s not really the question patients want answered. Patients want to know how much longer they can expect to live if they take a statin every day for the rest of their lives. Is it weeks? months? years? decades?
Last year I spent a couple of months working as a physician in a geriatric hospital, i.e. a hospital that specializes in taking care of elderly people. One thing that struck me particularly was the large number of medications each patient was on. I don’t think it would be much of an exaggeration to say that the average patient had ten or more medications that they were taking on a daily basis.
Is there any life left in the cholesterol hypothesis (a.k.a. the lipid hypothesis)? Is there anything left for serious scientists to cling to or is time for its mouldering corpse to end up on the trash heap of medical history, alongside lobotomy, bloodletting and the theory of the four humors? I was asked this question by a reader of this blog recently, and as it happens, a systematic review was recently published in Evidence Based Medicine (my favorite medical journal, mainly because it is edited by the brilliant Dr. Carl Heneghan) that definitively answers this question, so I thought it would be interesting to go through what the evidence says together.