Novavax covid vaccine safe and effective?

I’ve been getting frequent requests for at least the last six months to write about the Novavax covid vaccine. I’ve been resisting, mainly because it’s seemed uncertain whether it would ever actually be approved in the western world. Now that it’s been approved for use in the EU, however, that has changed, and I figure that I can put it off no longer.

I guess … Read more

Covid: Vaccine vs infection myocarditis risk

It’s been clear that the Pfizer and Moderna covid vaccines cause myocarditis for some time. What hasn’t been clear, though, is whether the risk of myocarditis after vaccination is greater than it is after infection. If the risk after infection is even greater than it is after vaccination, then a pretty good case can be made for not worrying too much about vaccine induced myocarditis, … Read more

Is fluvoxamine effective against covid-19?

Fluvoxamine is an anti-depressant drug that belongs to the class of drugs known as SSRI’s (selective serotonin reuptake inhibitors). It’s normally used to treat depression and anxiety. Lately, there’s been a lot of discussion over whether fluvoxamine might be effective as a treatment for covid-19.

Wait, what?!

Yes, that was my initial reaction. Why would an anti-depressant have any role in treating covid-19?

Well, apart … Read more

Covid-19: a new look at vitamin D

I’ve written about vitamin D as a potential treatment for covid-19 a couple of times before. In September of 2020 I wrote about a Spanish randomized trial that showed a massive reduction in ICU admissions in hospitalized patients treated with 25-hydroxyvitamin D (a part-activated form of vitamin D). However, that study had some major weaknesses – it was completely unblinded and it was small. In … Read more

Covid: the surprising fourth wave

I was surprised, at first, when many heavily vaccinated countries were hit by a new wave of covid-19 at the beginning of autumn. I was surprised, that is, until I started to see studies coming out that showed that the protection offered by the vaccines is far less impressive than was initially thought, and drops to low levels after just a few months.

In … Read more

Covid: How long does vaccine based immunity last?

It’s unfortunate that the drug companies decided to end their trials early, by giving active covid vaccine to the members of the placebo group after just a few months. It means that there is no long term follow-up of the covid vaccines from randomized trials, and there never will be. This means that we are instead forced to rely entirely on observational data as we … Read more